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HomoloGene:100661. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

KAT5,  H.sapiens
K(lysine) acetyltransferase 5
NP_874369.1
546 aa
KAT5,  P.troglodytes
K(lysine) acetyltransferase 5
XP_001170117.1
513 aa
KAT5,  C.lupus
K(lysine) acetyltransferase 5
XP_005631525.1
546 aa
KAT5,  B.taurus
K(lysine) acetyltransferase 5
NP_001178995.1
513 aa
Kat5,  M.musculus
K(lysine) acetyltransferase 5
NP_848752.1
513 aa
Kat5,  R.norvegicus
K(lysine) acetyltransferase 5
NP_001005872.1
513 aa
kat5,  X.tropicalis
K(lysine) acetyltransferase 5
NP_001072274.1
506 aa
zgc:92510,  D.rerio
zgc:92510
NP_001002365.1
541 aa
htatip,  D.rerio
HIV-1 tat interactive protein, homolog (human)
NP_001013327.2
538 aa
Tip60,  D.melanogaster
Tip60
NP_001259234.1
541 aa
AgaP_AGAP001539,  A.gambiae
AgaP_AGAP001539
XP_321583.5
457 aa
mys-1,  C.elegans
mys-1
NP_504796.1
458 aa
ESA1,  S.cerevisiae
ESA1
NP_014887.3
445 aa
KLLA0F11209g,  K.lactis
KLLA0F11209g
XP_455590.1
439 aa
AGOS_ACR138W,  E.gossypii
AGOS_ACR138W
NP_983540.2
435 aa
mst1,  S.pombe
mst1
NP_594630.1
463 aa
MGG_04133,  M.oryzae
MGG_04133
XP_003719696.1
534 aa
NCU05218,  N.crassa
NCU05218
XP_962217.1
506 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

RVBs are required for assembling a functional TIP60 complex.
Jha S, et al. Mol Cell Biol 33, 1164-74 (2013).
TIP60 as a potential marker for the malignancy of gastric cancer.
Sakuraba K, et al. Anticancer Res 31, 77-9 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tudor-knot (pfam11717)
  RNA binding activity-knot of a chromodomain.
PHA01732 (PHA01732)
  proline-rich protein.
Tudor-knot (pfam11717)
  RNA binding activity-knot of a chromodomain.
Myb_Cef (pfam11831)
  pre-mRNA splicing factor component.
NAT_SF (cl17182)
  N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate.
CHROMO (cl17459)
  Chromatin organization modifier (chromo) domain is a conserved region of around 50 amino acids found in a variety of chromosomal proteins, which appear to play a role in the functional organization of the eukaryotic nucleus. Experimental evidence implicates the chromo domain in the binding activity of these proteins to methylated histone tails and maybe RNA. May occur as single instance, in a tandem arrangement or followd by a related "chromo shadow" domain.
MOZ_SAS (cl19766)
  MOZ/SAS family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Kat5 includes H.sapiens KAT5 and R.norvegicus Kat5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 10 species)
Actinopterygii - bony fishes (12 transcripts, 7 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Aves - birds (3 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 11 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (3 transcripts, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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