Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:4701. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TXNRD2,  H.sapiens
thioredoxin reductase 2
NP_006431.2
524 aa
TXNRD2,  P.troglodytes
thioredoxin reductase 2
XP_001166615.2
482 aa
TXNRD2,  M.mulatta
thioredoxin reductase 2
NP_001152971.1
524 aa
TXNRD2,  C.lupus
thioredoxin reductase 2
XP_005636641.1
490 aa
TXNRD2,  B.taurus
thioredoxin reductase 2
NP_777051.1
511 aa
Txnrd2,  M.musculus
thioredoxin reductase 2
NP_038739.2
527 aa
Txnrd2,  R.norvegicus
thioredoxin reductase 2
NP_072106.1
526 aa
TXNRD2,  G.gallus
thioredoxin reductase 2
NP_001116163.1
518 aa
txnrd2,  X.tropicalis
thioredoxin reductase 2
NP_001120487.1
502 aa
Trxr-1,  D.melanogaster
Thioredoxin reductase-1
NP_727252.1
508 aa
Trxr-2,  D.melanogaster
thioredoxin reductase 2
NP_524216.1
516 aa
TRXR,  A.gambiae
TRXR
XP_003437030.1
502 aa
trxr-2,  C.elegans
trxr-2
NP_498971.1
503 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Selenium in thioredoxin reductase: a mechanistic perspective.
Lacey BM, et al. Biochemistry 47, 12810-21 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NAD_binding_8 (pfam13450)
  NAD(P)-binding Rossmann-like domain.
Pyr_redox (pfam00070)
  Pyridine nucleotide-disulphide oxidoreductase.
Pyr_redox_dim (pfam02852)
  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
NADB_Rossmann (cl09931)
  Rossmann-fold NAD(P)(+)-binding proteins.
GlpB (cl17730)
  Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism].
Pyr_redox (pfam00070)
  Pyridine nucleotide-disulphide oxidoreductase.
Pyr_redox_dim (pfam02852)
  Pyridine nucleotide-disulphide oxidoreductase, dimerization domain.
FMT_C_like (cl14785)
  Carboxy-terminal domain of Formyltransferase and similar domains.
NAD_binding_8 (cl19134)
  NAD(P)-binding Rossmann-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Txnrd2 includes H.sapiens TXNRD2 and R.norvegicus Txnrd2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 11 species)
Actinopterygii - bony fishes (5 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (16 transcripts, 12 species)
Arachnida - arachnids (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Porifera
Demospongiae - sponges (2 transcripts, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (3 transcripts, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

Support Center