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HomoloGene:20155. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GPX1,  H.sapiens
glutathione peroxidase 1
NP_000572.2
203 aa
GPX1,  P.troglodytes
glutathione peroxidase 1
NP_001070980.2
201 aa
GPX1,  M.mulatta
glutathione peroxidase 1
NP_001152770.1
198 aa
GPX1,  C.lupus
glutathione peroxidase 1
NP_001108591.1
205 aa
GPX1,  B.taurus
glutathione peroxidase 1
NP_776501.1
205 aa
Gpx1,  M.musculus
glutathione peroxidase 1
NP_032186.2
201 aa
Gpx1,  R.norvegicus
glutathione peroxidase 1
NP_110453.3
201 aa
GPX1,  G.gallus
glutathione peroxidase 1
NP_001264782.1
195 aa
gpx1,  X.tropicalis
glutathione peroxidase 1
NP_001015740.2
195 aa
gpx1b,  D.rerio
glutathione peroxidase 1b
NP_001004634.2
190 aa
gpx1a,  D.rerio
glutathione peroxidase 1a
NP_001007282.2
191 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hemolytic anemia due to glutathione peroxidase deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Glutathione peroxidase-1 reduces influenza A virus-induced lung inflammation.
Yatmaz S, et al. Am J Respir Cell Mol Biol 48, 17-26 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Thioredoxin_like (cl00388)
  Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gpx1 includes H.sapiens GPX1 and R.norvegicus Gpx1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (22 transcripts, 10 species)
Mammalia - mammals (21 transcripts, 17 species)
Aves - birds (4 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (3 transcripts, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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