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HomoloGene:377. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

OXCT1,  H.sapiens
3-oxoacid CoA transferase 1
NP_000427.1
520 aa
OXCT1,  P.troglodytes
3-oxoacid CoA transferase 1
XP_001137948.1
520 aa
OXCT1,  M.mulatta
3-oxoacid CoA transferase 1
XP_001114587.1
169 aa
OXCT1,  C.lupus
3-oxoacid CoA transferase 1
XP_536487.2
594 aa
OXCT1,  B.taurus
3-oxoacid CoA transferase 1
NP_001069538.1
520 aa
Oxct1,  M.musculus
3-oxoacid CoA transferase 1
NP_077150.1
520 aa
Oxct1,  R.norvegicus
3-oxoacid CoA transferase 1
NP_001121052.1
520 aa
OXCT1,  G.gallus
3-oxoacid CoA transferase 1
NP_001006578.2
517 aa
oxct1,  X.tropicalis
3-oxoacid CoA transferase 1
NP_001007927.1
530 aa
oxct1a,  D.rerio
3-oxoacid CoA transferase 1a
NP_001007292.1
525 aa
oxct1b,  D.rerio
3-oxoacid CoA transferase 1b
NP_001070618.1
526 aa
CG1140,  D.melanogaster
CG1140
NP_647683.1
516 aa
AgaP_AGAP006096,  A.gambiae
AgaP_AGAP006096
XP_316153.4
524 aa
C05C10.3,  C.elegans
C05C10.3
NP_496144.1
521 aa
MGG_11480,  M.oryzae
MGG_11480
XP_003718114.1
526 aa
NCU06881,  N.crassa
NCU06881
XP_959228.1
516 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Succinyl CoA:3-oxoacid CoA transferase deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Successful adaptation to ketosis by mice with tissue-specific deficiency of ketone body oxidation.
Cotter DG, et al. Am J Physiol Endocrinol Metab 304, E363-74 (2013).
Obligate role for ketone body oxidation in neonatal metabolic homeostasis.
Cotter DG, et al. J Biol Chem 286, 6902-10 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CoA_trans (cl17247)
  Coenzyme A transferase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Oxct1 includes H.sapiens OXCT1 and R.norvegicus Oxct1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (24 transcripts, 15 species)
Actinopterygii - bony fishes (19 transcripts, 10 species)
Ascidiacea - tunicates (3 transcripts, 2 species)
Amniota - vertebrates (2 transcripts, 1 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (13 transcripts, 11 species)
Arachnida - arachnids (3 transcripts, 1 species)
Malacostraca - crustaceans (2 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (5 transcripts, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (7 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Ciliophora
Oligohymenophorea - ciliates (8 transcripts, 2 species)

Streptophyta
Liliopsida - monocots (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

 

 

 

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