Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:344. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ERCC2,  H.sapiens
excision repair cross-complementation group 2
NP_000391.1
760 aa
ERCC2,  P.troglodytes
excision repair cross-complementing rodent repair deficiency, complementation group 2
NP_001233519.1
760 aa
LOC715485,  M.mulatta
TFIIH basal transcription factor complex helicase subunit-like
XP_002808245.1
739 aa
ERCC2,  C.lupus
excision repair cross-complementing rodent repair deficiency, complementation group 2
XP_541562.3
760 aa
ERCC2,  B.taurus
excision repair cross-complementing rodent repair deficiency, complementation group 2
NP_001096787.1
760 aa
Ercc2,  M.musculus
excision repair cross-complementing rodent repair deficiency, complementation group 2
NP_031975.2
760 aa
Ercc2,  R.norvegicus
excision repair cross-complementing rodent repair deficiency, complementation group 2
NP_001166280.1
760 aa
ercc2,  X.tropicalis
excision repair cross-complementing rodent repair deficiency, complementation group 2
NP_001008131.1
760 aa
ercc2,  D.rerio
excision repair cross-complementing rodent repair deficiency, complementation group 2
NP_957220.1
643 aa
Xpd,  D.melanogaster
Xeroderma pigmentosum D
NP_726036.2
769 aa
AgaP_AGAP002988,  A.gambiae
AgaP_AGAP002988
XP_311900.4
760 aa
Y50D7A.2,  C.elegans
Y50D7A.2
NP_497182.2
606 aa
RAD3,  S.cerevisiae
RAD3
NP_011098.3
778 aa
KLLA0C17776g,  K.lactis
KLLA0C17776g
XP_452994.1
778 aa
AGOS_AGR114C,  E.gossypii
AGOS_AGR114C
NP_986780.1
774 aa
rad15,  S.pombe
rad15
NP_593025.1
772 aa
MGG_03132,  M.oryzae
MGG_03132
XP_003716866.1
795 aa
NCU01625,  N.crassa
NCU01625
XP_956536.2
796 aa
UVH6,  A.thaliana
UVH6
NP_171818.1
758 aa
Os05g0144800,  O.sativa
Os05g0144800
NP_001054627.1
758 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Xeroderma pigmentosum, group D.
Trichothiodystrophy.
Cerebrooculofacioskeletal syndrome 2.



Publications
Articles associated with genes and sequences of this homology group.

Analysis of mutations in the XPD gene in a patient with brittle hair.
Shin S, et al. Ann Clin Lab Sci 43, 323-7 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DUF1227 (pfam06777)
  Protein of unknown function (DUF1227).
P-loop_NTPase (cl09099)
  P-loop containing Nucleoside Triphosphate Hydrolases.
DEXDc (cl17251)
  DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Helicase_C_2 (cl17460)
  Helicase C-terminal domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ercc2 includes H.sapiens ERCC2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (8 transcripts, 8 species)
Ascidiacea - tunicates (5 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (7 transcripts, 7 species)
Arachnida - arachnids (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (18 transcripts, 15 species)
Liliopsida - monocots (8 transcripts, 8 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Bryopsida - mosses (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

 

 

 

Support Center