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HomoloGene:21165. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NR1H3,  H.sapiens
nuclear receptor subfamily 1, group H, member 3
NP_005684.2
447 aa
NR1H3,  P.troglodytes
nuclear receptor subfamily 1, group H, member 3
XP_521906.1
447 aa
NR1H3,  M.mulatta
nuclear receptor subfamily 1, group H, member 3
XP_001109209.1
447 aa
NR1H3,  C.lupus
nuclear receptor subfamily 1, group H, member 3
XP_005631319.1
447 aa
NR1H3,  B.taurus
nuclear receptor subfamily 1, group H, member 3
NP_001014861.1
447 aa
Nr1h3,  M.musculus
nuclear receptor subfamily 1, group H, member 3
NP_001171201.1
445 aa
Nr1h3,  R.norvegicus
nuclear receptor subfamily 1, group H, member 3
NP_113815.2
445 aa
NR1H3,  G.gallus
nuclear receptor subfamily 1, group H, member 3
NP_989873.1
409 aa
nr1h3,  D.rerio
nuclear receptor subfamily 1, group H, member 3
NP_001017545.1
412 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Foam cell specific LXRα ligand.
Feldmann R, et al. PLoS One 8, e57311 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nr1h3 includes H.sapiens NR1H3 and R.norvegicus Nr1h3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 12 species)
Actinopterygii - bony fishes (8 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 9 species)
Arachnida - arachnids (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 2 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

 

 

 

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