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HomoloGene:4058. Gene conserved in Tetrapoda Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

KRT7,  H.sapiens
keratin 7
469 aa
KRT7,  P.troglodytes
keratin 7
469 aa
KRT7,  M.mulatta
keratin 7
469 aa
KRT7,  C.lupus
keratin 7
468 aa
KRT7,  B.taurus
keratin 7
466 aa
Krt7,  M.musculus
keratin 7
457 aa
Krt7,  R.norvegicus
keratin 7
457 aa
KRT7,  G.gallus
keratin 7
492 aa
krt5.7,  X.tropicalis
keratin 5, gene 7
523 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Generation and characterisation of keratin 7 (K7) knockout mice.
Sandilands A, et al. PLoS One 8, e64404 (2013).
Heterogeneity of cytokeratin 7 expression in pagetoid Bowen's disease.
Misago N, et al. J Cutan Pathol 39, 724-6 (2012).
Hepatocyte cytokeratin 7 expression in chronic allograft rejection.
Bellizzi AM, et al. Am J Clin Pathol 135, 238-44 (2011).
Toker cells revisited.
Nofech-Mozes S & Hanna W. Breast J 15, 394-8 (2009).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Filament (pfam00038)
  Intermediate filament protein.
RapA_C (pfam12137)
  RNA polymerase recycling family C-terminal.
DUF4081 (pfam13312)
  Domain of unknown function (DUF4081).
Prefoldin (cl09111)
  Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Krt7 includes H.sapiens KRT7 and R.norvegicus Krt7.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (15 transcripts, 13 species)
Actinopterygii - bony fishes (5 transcripts, 3 species)
Amniota - vertebrates (2 transcripts, 1 species)




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