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HomoloGene:55733. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TXNRD1,  H.sapiens
thioredoxin reductase 1
NP_001087240.1
649 aa
TXNRD1,  P.troglodytes
thioredoxin reductase 1
NP_001116141.1
499 aa
TXNRD1,  M.mulatta
thioredoxin reductase 1
XP_002798903.1
596 aa
TXNRD1,  C.lupus
thioredoxin reductase 1
NP_001116145.1
655 aa
TXNRD1,  B.taurus
thioredoxin reductase 1
NP_777050.1
499 aa
Txnrd1,  M.musculus
thioredoxin reductase 1
NP_001035988.1
613 aa
Txnrd1,  R.norvegicus
thioredoxin reductase 1
NP_113802.2
499 aa
TXNRD1,  G.gallus
thioredoxin reductase 1
NP_001025933.2
499 aa
txnrd1,  X.tropicalis
thioredoxin reductase 1
NP_001243400.1
653 aa
GR1,  A.thaliana
GR1
NP_001118688.1
499 aa
Os02g0813500,  O.sativa
Os02g0813500
NP_001048485.1
496 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Is thioredoxin reductase involved in the defense against DNA fragmentation in varicocele?
Ă–zdemirler Erata G, et al. Asian J Androl 15, 518-22 (2013).
Tissue and plasma thioredoxin reductase expressions in patients with glioblastoma multiforme.
Kemerdere R, et al. J Neurol Surg A Cent Eur Neurosurg 74, 234-8 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Pyr_redox (pfam00070)
  Pyridine nucleotide-disulphide oxidoreductase.
Pyr_redox_dim (pfam02852)
  Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain.
Pyr_redox (pfam00070)
  Pyridine nucleotide-disulphide oxidoreductase.
Pyr_redox_dim (pfam02852)
  Pyridine nucleotide-disulphide oxidoreductase, dimerization domain.
Thioredoxin_like (cl00388)
  Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold.
NAD_binding_8 (cl19134)
  NAD(P)-binding Rossmann-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Txnrd1 includes H.sapiens TXNRD1 and R.norvegicus Txnrd1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (44 transcripts, 33 species)
Liliopsida - monocots (10 transcripts, 9 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Bryopsida - mosses (2 transcripts, 1 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (6 transcripts, 2 species)

Chordata
Mammalia - mammals (19 transcripts, 15 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (5 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (4 transcripts, 1 species)
Trematoda - flatworms (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (9 transcripts, 2 species)

Oomycetes
Peronosporales - oomycetes (2 transcripts, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

 

 

 

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