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HomoloGene:38291. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

XPOT,  H.sapiens
exportin, tRNA
NP_009166.2
962 aa
XPOT,  P.troglodytes
exportin, tRNA
XP_509193.2
962 aa
XPOT,  M.mulatta
exportin, tRNA
XP_001116910.1
962 aa
XPOT,  C.lupus
exportin, tRNA
XP_005625640.1
962 aa
XPOT,  B.taurus
exportin, tRNA (nuclear export receptor for tRNAs)
NP_001193005.1
962 aa
Xpot,  M.musculus
exportin, tRNA (nuclear export receptor for tRNAs)
NP_001074525.1
962 aa
XPOT,  G.gallus
exportin, tRNA (nuclear export receptor for tRNAs)
NP_001186535.1
962 aa
xpot,  X.tropicalis
exportin, tRNA
NP_001135715.1
962 aa
xpot,  D.rerio
exportin, tRNA (nuclear export receptor for tRNAs)
NP_001038317.1
971 aa
xpo-3,  C.elegans
xpo-3
NP_501320.2
950 aa
LOS1,  S.cerevisiae
LOS1
NP_012717.1
1100 aa
KLLA0B14036g,  K.lactis
KLLA0B14036g
XP_452156.1
1063 aa
AGOS_AFR424C,  E.gossypii
AGOS_AFR424C
NP_985971.2
1051 aa
los1,  S.pombe
los1
NP_596516.1
978 aa
MGG_10127,  M.oryzae
MGG_10127
XP_003713776.1
1027 aa
NCU11169,  N.crassa
NCU11169
XP_956187.2
1026 aa
PSD,  A.thaliana
PSD
NP_177400.2
988 aa
Os07g0613300,  O.sativa
Os07g0613300
NP_001060255.1
980 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

PAUSED encodes the Arabidopsis exportin-t ortholog.
Hunter CA, et al. Plant Physiol 132, 2135-43 (2003).
Maf1 protein, repressor of RNA polymerase III, indirectly affects tRNA processing.
Karkusiewicz I, et al. J Biol Chem 286, 39478-88 (2011).
Export and transport of tRNA are coupled to a multi-protein complex.
Kruse C, et al. Biochem J 346 Pt 1, 107-15 (2000).
tRNA nuclear export in saccharomyces cerevisiae: in situ hybridization analysis.
Sarkar S & Hopper AK. Mol Biol Cell 9, 3041-55 (1998).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Xpo1 (pfam08389)
  Exportin 1-like protein.
Xpo1 (pfam08389)
  Exportin 1-like protein.
IBN_N (cl04271)
  Members of the importin-beta (karyopherin-beta) family can bind and transport cargo by themselves, or can form heterodimers with importin-alpha. As part of a heterodimer, importin-beta mediates interactions with the pore complex, while importin-alpha acts as an adaptor protein to bind the nuclear localisation signal (NLS) on the cargo through the classical NLS import of proteins. Importin-beta is a helicoidal molecule constructed from 19 HEAT repeats. Many nuclear pore proteins contain FG sequence repeats that can bind to HEAT repeats within importins.. which is important for importin-beta mediated transport.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Xpot includes H.sapiens XPOT and R.norvegicus Xpot.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (18 transcripts, 12 species)
Actinopterygii - bony fishes (8 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (2 transcripts, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (21 transcripts, 15 species)
Liliopsida - monocots (7 transcripts, 7 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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