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HomoloGene:39203. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GNAO1,  H.sapiens
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
NP_066268.1
354 aa
GNAO1,  P.troglodytes
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
XP_510976.3
354 aa
GNAO1,  M.mulatta
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
XP_001096035.2
354 aa
GNAO1,  C.lupus
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
XP_005617599.1
354 aa
GNAO1,  B.taurus
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
NP_776750.1
354 aa
Gnao1,  M.musculus
guanine nucleotide binding protein, alpha O
NP_034438.1
354 aa
Gnao1,  R.norvegicus
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
NP_059023.1
354 aa
GNAO1,  G.gallus
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
NP_001264479.1
354 aa
gnao1,  X.tropicalis
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
NP_001016995.1
354 aa
gnao1a,  D.rerio
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O, a
NP_957081.1
354 aa
G-oalpha47A,  D.melanogaster
G protein oalpha 47A
NP_724934.1
354 aa
AgaP_AGAP005773,  A.gambiae
AgaP_AGAP005773
XP_315788.3
355 aa
goa-1,  C.elegans
goa-1
NP_492108.1
354 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Gαo is required for L-canavanine detection in Drosophila.
Devambez I, et al. PLoS One 8, e63484 (2013).
Molecular basis of a novel oncogenic mutation in GNAO1.
Garcia-Marcos M, et al. Oncogene 30, 2691-6 (2011).
Go contributes to olfactory reception in Drosophila melanogaster.
Chatterjee A, et al. BMC Physiol 9, 22 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
P-loop_NTPase (cl09099)
  P-loop containing Nucleoside Triphosphate Hydrolases.
Ras_like_GTPase (cl17170)
  Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gnao1 includes H.sapiens GNAO1 and R.norvegicus Gnao1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (14 transcripts, 8 species)
Mammalia - mammals (12 transcripts, 11 species)
Amphibia - amphibians (4 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 1 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 7 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (5 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (2 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

 

 

 

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