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HomoloGene:37311. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SLC5A5,  H.sapiens
solute carrier family 5 (sodium/iodide cotransporter), member 5
NP_000444.1
643 aa
SLC5A5,  P.troglodytes
solute carrier family 5 (sodium iodide symporter), member 5
XP_524154.2
643 aa
SLC5A5,  C.lupus
solute carrier family 5 (sodium/iodide cotransporter), member 5
XP_541946.3
642 aa
SLC5A5,  B.taurus
solute carrier family 5 (sodium iodide symporter), member 5
XP_002688618.2
769 aa
Slc5a5,  M.musculus
solute carrier family 5 (sodium iodide symporter), member 5
NP_444478.2
618 aa
Slc5a5,  R.norvegicus
solute carrier family 5 (sodium/iodide cotransporter), member 5
NP_443215.2
618 aa
SLC5A5,  G.gallus
solute carrier family 5 (sodium iodide symporter), member 5
XP_429095.4
737 aa
slc5a5,  X.tropicalis
solute carrier family 5 (sodium/iodide cotransporter), member 5
NP_001116937.1
600 aa
slc5a5,  D.rerio
solute carrier family 5 (sodium iodide symporter), member 5
NP_001082860.1
601 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hypothyroidism, congenital.



Publications
Articles associated with genes and sequences of this homology group.

The sodium/iodide symporter: state of the art of its molecular characterization.
Darrouzet E, et al. Biochim Biophys Acta 1838, 244-53 (2014).
Radioiodide uptake and sodium iodide symporter expression in breast carcinoma.
Damle AA, et al. Indian J Exp Biol 49, 416-22 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SLC5-6-like_sbd (cl00456)
  Solute carrier families 5 and 6-like; solute binding domain.
SLC5-6-like_sbd (cl00456)
  Solute carrier families 5 and 6-like; solute binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc5a5 includes H.sapiens SLC5A5 and R.norvegicus Slc5a5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 9 species)
Actinopterygii - bony fishes (4 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)

 

 

 

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