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HomoloGene:91. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

EMD,  H.sapiens
emerin
NP_000108.1
254 aa
EMD,  P.troglodytes
emerin
XP_521335.3
239 aa
EMD,  M.mulatta
emerin
XP_001090376.1
258 aa
EMD,  C.lupus
emerin
XP_549369.4
260 aa
EMD,  B.taurus
emerin
NP_976237.1
260 aa
Emd,  M.musculus
emerin
NP_031953.1
259 aa
Emd,  R.norvegicus
emerin
NP_037080.1
260 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Emery-Dreifuss muscular dystrophy.



Publications
Articles associated with genes and sequences of this homology group.

Emery-Dreifuss humeroperoneal muscular dystrophy: cardiac manifestations.
Parmar MS & Parmar KS. Can J Cardiol 28, 516.e1-3 (2012).
Limb-girdle muscular dystrophy due to emerin gene mutations.
Ura S, et al. Arch Neurol 64, 1038-41 (2007).
Multiple roles for emerin: implications for Emery-Dreifuss muscular dystrophy.
Holaska JM & Wilson KL. Anat Rec A Discov Mol Cell Evol Biol 288, 676-80 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LEM (pfam03020)
  LEM domain.
LEM (cl02649)
  LEM (Lap2/Emerin/Man1) domain found in emerin, lamina-associated polypeptide 2 (LAP2), inner nuclear membrane protein Man1 and similar proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Emd includes H.sapiens EMD and R.norvegicus Emd.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 13 species)

 

 

 

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