Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:7979. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TNFSF12,  H.sapiens
tumor necrosis factor (ligand) superfamily, member 12
NP_003800.1
249 aa
TNFSF12,  P.troglodytes
tumor necrosis factor (ligand) superfamily, member 12
NP_001192058.1
249 aa
TNFSF12,  C.lupus
tumor necrosis factor (ligand) superfamily, member 12
NP_001192097.1
249 aa
TNFSF12,  B.taurus
tumor necrosis factor (ligand) superfamily, member 12
NP_001192072.1
248 aa
Tnfsf12,  M.musculus
tumor necrosis factor (ligand) superfamily, member 12
NP_035744.1
249 aa
Tnfsf12,  R.norvegicus
tumor necrosis factor ligand superfamily member 12
NP_001001513.2
249 aa
tnfsf12,  D.rerio
tumor necrosis factor (ligand) superfamily, member 12
NP_001070075.1
236 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Antibody deficiency associated with an inherited autosomal dominant mutation in TWEAK.
Wang HY, et al. Proc Natl Acad Sci U S A 110, 5127-32 (2013).
Role of TWEAK in lupus nephritis: a bench-to-bedside review.
Michaelson JS, et al. J Autoimmun 39, 130-42 (2012).
Urinary TWEAK level as a marker of lupus nephritis activity in 46 cases.
Xuejing Z, et al. J Biomed Biotechnol 2012, 359647 (2012).
Evaluation of serum TWEAK concentration in patients with acute pancreatitis.
Koçak E, et al. Scand J Clin Lab Invest 72, 192-6 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TNF (cl00147)
  Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...
TNF (cl00147)
  Tumor Necrosis Factor; TNF superfamily members include the cytokines: TNF (TNF-alpha), LT (lymphotoxin-alpha, TNF-beta), CD40 ligand, Apo2L (TRAIL), Fas ligand, and osteoprotegerin (OPG) ligand. These proteins generally have an intracellular N-terminal ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tnfsf12 includes H.sapiens TNFSF12 and R.norvegicus Tnfsf12.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 6 species)
Actinopterygii - bony fishes (3 transcripts, 3 species)

 

 

 

Support Center