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HomoloGene:82414. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

FOXK1,  H.sapiens
forkhead box K1
733 aa
FOXK1,  P.troglodytes
forkhead box K1
733 aa
FOXK1,  C.lupus
forkhead box K1
611 aa
FOXK1,  B.taurus
forkhead box K1
608 aa
Foxk1,  M.musculus
forkhead box K1
719 aa
Foxk1,  R.norvegicus
forkhead box K1
719 aa
FOXK1,  G.gallus
forkhead box K1
539 aa
foxk1,  D.rerio
forkhead box K1
639 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Identification and characterization of human FOXK1 gene in silico.
Katoh M & Katoh M. Int J Mol Med 14, 127-32 (2004).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Herpes_UL32 (pfam06070)
  Herpesvirus large structural phosphoprotein UL32.
FH (cl00061)
  Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA ...
FHA (cl00062)
  Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Foxk1 includes H.sapiens FOXK1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (12 transcripts, 9 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Insecta - insects (3 transcripts, 3 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Gastropoda - gastropods (1 transcript, 1 species)

Echinoidea - sea urchins (1 transcript, 1 species)




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