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HomoloGene:96916. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ATR,  H.sapiens
ataxia telangiectasia and Rad3 related
NP_001175.2
2644 aa
ATR,  P.troglodytes
ataxia telangiectasia and Rad3 related
XP_516792.3
2651 aa
ATR,  M.mulatta
ataxia telangiectasia and Rad3 related
XP_001112149.1
2644 aa
ATR,  C.lupus
ataxia telangiectasia and Rad3 related
XP_003639878.1
2644 aa
ATR,  B.taurus
ataxia telangiectasia and Rad3 related
XP_002685103.2
2644 aa
Atr,  M.musculus
ataxia telangiectasia and Rad3 related
NP_063917.1
2641 aa
Atr,  R.norvegicus
ataxia telangiectasia and Rad3 related
XP_003750609.1
2636 aa
ATR,  G.gallus
ataxia telangiectasia and Rad3 related
XP_003641789.1
2646 aa
atr,  X.tropicalis
ataxia telangiectasia and Rad3 related
XP_002937136.2
2645 aa
atr,  D.rerio
ataxia telangiectasia and Rad3 related
XP_696163.5
2633 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Seckel syndrome 1.



Publications
Articles associated with genes and sequences of this homology group.

Running-induced anxiety is dependent on increases in hippocampal neurogenesis.
Onksen JL, et al. Genes Brain Behav 11, 529-38 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FATC (pfam02260)
  FATC domain.
FAT (pfam02259)
  FAT domain.
FAT (pfam02259)
  FAT domain.
FATC (pfam02260)
  FATC domain.
PI3Kc_like (cl00119)
  Phosphoinositide 3-kinase (PI3K)-like family, catalytic domain; The PI3K-like catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs), ...
UME (cl06893)
  This domain is characteristic of UVSB PI-3 kinase, MEI-41 and ESR1.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atr includes H.sapiens ATR.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (28 transcripts, 13 species)
Actinopterygii - bony fishes (14 transcripts, 8 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (3 transcripts, 3 species)
Coniferopsida - conifers (2 transcripts, 2 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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