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HomoloGene:6741. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PI4KB,  H.sapiens
phosphatidylinositol 4-kinase, catalytic, beta
NP_002642.1
828 aa
PI4KB,  P.troglodytes
phosphatidylinositol 4-kinase, catalytic, beta
XP_001171634.2
828 aa
PI4KB,  M.mulatta
phosphatidylinositol 4-kinase beta-like
XP_001106422.2
816 aa
PI4KB,  C.lupus
phosphatidylinositol 4-kinase, catalytic, beta
XP_540314.3
828 aa
PI4KB,  B.taurus
phosphatidylinositol 4-kinase, catalytic, beta
NP_777208.1
801 aa
Pi4kb,  M.musculus
phosphatidylinositol 4-kinase, catalytic, beta polypeptide
NP_780565.2
801 aa
Pi4kb,  R.norvegicus
phosphatidylinositol 4-kinase, catalytic, beta
NP_112345.1
816 aa
LOC100859723,  G.gallus
phosphatidylinositol 4-kinase beta-like
XP_003642722.2
890 aa
PI4KB,  G.gallus
phosphatidylinositol 4-kinase, catalytic, beta
XP_423394.4
890 aa
pi4kb,  X.tropicalis
phosphatidylinositol 4-kinase, catalytic, beta
NP_001096204.1
806 aa
pi4kb,  D.rerio
phosphatidylinositol 4-kinase, catalytic, beta
NP_001030149.2
835 aa
fwd,  D.melanogaster
four wheel drive
NP_728518.1
1674 aa
AgaP_AGAP007512,  A.gambiae
AgaP_AGAP007512
XP_001687908.1
1779 aa
pifk-1,  C.elegans
pifk-1
NP_508177.2
666 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The lipid kinase PI4KIIIβ preserves lysosomal identity.
Sridhar S, et al. EMBO J 32, 324-39 (2013).
Mammalian phosphatidylinositol 4-kinases.
Heilmeyer LM Jr, et al. IUBMB Life 55, 59-65 (2003).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PI3Kc_like (cl00119)
  Phosphoinositide 3-kinase (PI3K)-like family, catalytic domain; The PI3K-like catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs), ...
PI3Kc_like (cl00119)
  Phosphoinositide 3-kinase (PI3K)-like family, catalytic domain; The PI3K-like catalytic domain family is part of a larger superfamily that includes the catalytic domains of other kinases such as the typical serine/threonine/tyrosine protein kinases (PKs), ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pi4kb includes H.sapiens PI4KB and R.norvegicus Pi4kb.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (20 transcripts, 13 species)
Actinopterygii - bony fishes (9 transcripts, 6 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (6 transcripts, 5 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (6 transcripts, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (3 transcripts, 1 species)

Streptophyta
Eudicotyledons - eudicots (4 transcripts, 4 species)
Liliopsida - monocots (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 1 species)

 

 

 

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