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HomoloGene:22547. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

COL11A2,  H.sapiens
collagen, type XI, alpha 2
NP_542411.2
1736 aa
COL11A2,  M.mulatta
collagen alpha-2(XI) chain-like
XP_002808428.1
1676 aa
COL11A2,  C.lupus
collagen, type XI, alpha 2
XP_005627252.1
1733 aa
COL11A2,  B.taurus
collagen, type XI, alpha 2
NP_001039664.1
1736 aa
Col11a2,  M.musculus
collagen, type XI, alpha 2
NP_034056.1
1650 aa
Col11a2,  R.norvegicus
collagen, type XI, alpha 2
NP_997693.1
1617 aa
col11a2,  D.rerio
collagen type XI alpha-2
NP_001073461.1
1695 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Stickler syndrome, type III.
Otospondylomegaepiphyseal dysplasia.
Weissenbacher-Zweymuller syndrome.
Deafness, autosomal dominant 13.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
COLFI (pfam01410)
  Fibrillar collagen C-terminal domain.
COLFI (cl02436)
  Fibrillar collagen C-terminal domain.
LamG (cl17353)
  Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
Collagen (cl19732)
  Collagen triple helix repeat (20 copies).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Col11a2 includes H.sapiens COL11A2 and R.norvegicus Col11a2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 9 species)
Actinopterygii - bony fishes (4 transcripts, 3 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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