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HomoloGene:3254. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DUSP1,  H.sapiens
dual specificity phosphatase 1
NP_004408.1
367 aa
DUSP1,  P.troglodytes
dual specificity phosphatase 1
XP_527120.2
367 aa
DUSP1,  M.mulatta
dual specificity phosphatase 1
XP_001096004.1
367 aa
DUSP1,  C.lupus
dual specificity phosphatase 1
XP_005619503.1
492 aa
DUSP1,  B.taurus
dual specificity phosphatase 1
NP_001039917.1
367 aa
Dusp1,  M.musculus
dual specificity phosphatase 1
NP_038670.1
367 aa
Dusp1,  R.norvegicus
dual specificity phosphatase 1
NP_446221.2
367 aa
DUSP1,  G.gallus
dual specificity phosphatase 1
NP_001078828.1
369 aa
dusp1,  X.tropicalis
dual specificity phosphatase 1
NP_001005450.2
369 aa
dusp1,  D.rerio
dual specificity phosphatase 1
NP_998232.1
360 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RHOD (cl00125)
  Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...
DSPc (cl00053)
  Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
RHOD (cl00125)
  Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dusp1 includes H.sapiens DUSP1 and R.norvegicus Dusp1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 12 species)
Actinopterygii - bony fishes (10 transcripts, 9 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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