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HomoloGene:1196. Gene conserved in Amniota Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

IL10RA,  H.sapiens
interleukin 10 receptor, alpha
578 aa
IL10RA,  P.troglodytes
interleukin 10 receptor, alpha
578 aa
IL10RA,  M.mulatta
interleukin 10 receptor, alpha
590 aa
IL10RA,  C.lupus
interleukin 10 receptor, alpha
647 aa
IL10RA,  B.taurus
interleukin 10 receptor, alpha
584 aa
Il10ra,  M.musculus
interleukin 10 receptor, alpha
575 aa
Il10ra,  R.norvegicus
interleukin 10 receptor, alpha
569 aa
IL10RA,  G.gallus
interleukin 10 receptor, alpha
558 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Inflammatory bowel disease 28, autosomal recessive.

Articles associated with genes and sequences of this homology group.

Inflammation profile of four early onset Crohn patients.
Marcuzzi A, et al. Gene 493, 282-5 (2012).
The IL-10R1 S138G loss-of-function allele and ulcerative colitis.
Grundtner P, et al. Genes Immun 10, 84-92 (2009).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tissue_fac (pfam01108)
  Tissue factor.
Interfer-bind (pfam09294)
  Interferon-alpha/beta receptor, fibronectin type III.
FN3 (cl00065)
  Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Interfer-bind (pfam09294)
  Interferon-alpha/beta receptor, fibronectin type III.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Il10ra includes H.sapiens IL10RA and R.norvegicus Il10ra.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (5 transcripts, 5 species)
Aves - birds (1 transcript, 1 species)




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