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HomoloGene:37249. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ADA,  H.sapiens
adenosine deaminase
NP_000013.2
363 aa
ADA,  P.troglodytes
adenosine deaminase
XP_001144517.1
363 aa
ADA,  M.mulatta
adenosine deaminase
XP_001109908.2
363 aa
ADA,  C.lupus
adenosine deaminase
XP_005635156.1
363 aa
ADA,  B.taurus
adenosine deaminase
NP_776312.1
363 aa
Ada,  M.musculus
adenosine deaminase
NP_001258981.1
352 aa
Ada,  R.norvegicus
adenosine deaminase
NP_569083.1
352 aa
ADA,  G.gallus
adenosine deaminase
NP_001006290.1
357 aa
ada,  X.tropicalis
adenosine deaminase
NP_001011025.1
358 aa
ada,  D.rerio
adenosine deaminase
NP_001002646.1
362 aa
C06G3.5,  C.elegans
C06G3.5
NP_501087.1
391 aa
AAH1,  S.cerevisiae
AAH1
NP_014258.1
347 aa
KLLA0E23167g,  K.lactis
KLLA0E23167g
XP_454997.1
355 aa
dea2,  S.pombe
dea2
NP_595071.1
367 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Adenosine deaminase deficiency, partial.
Severe combined immunodeficiency due to ADA deficiency.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
metallo-dependent_hydrolases (cl00281)
  Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ada includes H.sapiens ADA and R.norvegicus Ada.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (8 transcripts, 7 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (2 transcripts, 1 species)

Arthropoda
Arachnida - arachnids (2 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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