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HomoloGene:41111. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RAB10,  H.sapiens
RAB10, member RAS oncogene family
NP_057215.3
200 aa
RAB10,  P.troglodytes
RAB10, member RAS oncogene family
XP_525714.2
200 aa
RAB10,  C.lupus
RAB10, member RAS oncogene family
NP_001003277.2
200 aa
RAB10,  B.taurus
RAB10, member RAS oncogene family
NP_001094758.1
200 aa
Rab10,  M.musculus
RAB10, member RAS oncogene family
NP_057885.1
200 aa
Rab10,  R.norvegicus
RAB10, member RAS oncogene family
NP_059055.2
200 aa
RAB10,  G.gallus
RAB10, member RAS oncogene family
NP_001026268.1
200 aa
rab10,  D.rerio
RAB10, member RAS oncogene family
NP_001002566.1
201 aa
Rab10,  D.melanogaster
Rab10
NP_523419.1
204 aa
AgaP_AGAP000671,  A.gambiae
AgaP_AGAP000671
XP_311197.3
204 aa
rab-10,  C.elegans
rab-10
NP_491857.1
201 aa
RAB8C,  A.thaliana
RAB8C
NP_195972.1
216 aa
RABE1e,  A.thaliana
RABE1e
NP_187601.1
218 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Rab10 GTPase regulates ER dynamics and morphology.
English AR & Voeltz GK. Nat Cell Biol 15, 169-78 (2013).
RAB-5 and RAB-10 cooperate to regulate neuropeptide release in Caenorhabditis elegans.
Sasidharan N, et al. Proc Natl Acad Sci U S A 109, 18944-9 (2012).
RAB-10-GTPase-mediated regulation of endosomal phosphatidylinositol-4,5-bisphosphate.
Shi A, et al. Proc Natl Acad Sci U S A 109, E2306-15 (2012).
Rab10 associates with primary cilia and the exocyst complex in renal epithelial cells.
Babbey CM, et al. Am J Physiol Renal Physiol 299, F495-506 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ras_like_GTPase (cl17170)
  Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rab10 includes H.sapiens RAB10 and R.norvegicus Rab10.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 13 species)
Actinopterygii - bony fishes (14 transcripts, 11 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Aves - birds (4 transcripts, 2 species)
Amphibia - amphibians (4 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 9 species)
Arachnida - arachnids (2 transcripts, 2 species)
Maxillopoda - crustaceans (2 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (3 transcripts, 1 species)
Trematoda - flatworms (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (3 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (2 transcripts, 1 species)
Eudicotyledons - eudicots (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

 

 

 

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