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HomoloGene:30976. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

F10,  H.sapiens
coagulation factor X
NP_000495.1
488 aa
F10,  P.troglodytes
coagulation factor X
XP_509746.2
488 aa
F10,  M.mulatta
coagulation factor X
NP_001098054.1
488 aa
F10,  C.lupus
coagulation factor X
XP_534191.1
486 aa
F10,  B.taurus
coagulation factor X
NP_001073682.1
492 aa
F10,  M.musculus
coagulation factor X
NP_031998.3
481 aa
F10,  R.norvegicus
coagulation factor X
NP_058839.1
482 aa
F10,  G.gallus
coagulation factor X
NP_990353.1
475 aa
f10,  X.tropicalis
coagulation factor 10
NP_001015728.1
464 aa
f10,  D.rerio
coagulation factor X
NP_958870.2
474 aa
CG11836,  D.melanogaster
CG11836
NP_001163718.3
281 aa
AgaP_AGAP004570,  A.gambiae
AgaP_AGAP004570
XP_313874.5
259 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Factor X deficiency.



Publications
Articles associated with genes and sequences of this homology group.

F10 gene hypomethylation, a putative biomarker for glioma prognosis.
Liu X, et al. J Neurooncol 107, 479-85 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Tryp_SPc (cd00190)
  Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
vWFA (cl00057)
  Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
Gla (cl02449)
  Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus F10 includes H.sapiens F10 and R.norvegicus F10.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (8 transcripts, 7 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 6 species)
Branchiopoda - crustaceans (6 transcripts, 1 species)
Arachnida - arachnids (2 transcripts, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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