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HomoloGene:30953. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

BTK,  H.sapiens
Bruton agammaglobulinemia tyrosine kinase
NP_001274273.1
693 aa
BTK,  P.troglodytes
Bruton agammaglobulinemia tyrosine kinase
XP_001139132.2
693 aa
BTK,  M.mulatta
Bruton agammaglobulinemia tyrosine kinase
XP_002806376.1
639 aa
BTK,  C.lupus
Bruton agammaglobulinemia tyrosine kinase
XP_549139.2
659 aa
BTK,  B.taurus
Bruton agammaglobulinemia tyrosine kinase
NP_001029761.1
659 aa
Btk,  M.musculus
Bruton agammaglobulinemia tyrosine kinase
NP_038510.2
659 aa
Btk,  R.norvegicus
Bruton agammaglobulinemia tyrosine kinase
NP_001007799.1
660 aa
BTK,  G.gallus
Bruton agammaglobulinemia tyrosine kinase
NP_989564.2
657 aa
btk,  X.tropicalis
Bruton agammaglobulinemia tyrosine kinase
NP_001123732.1
649 aa
btk,  D.rerio
Bruton agammaglobulinemia tyrosine kinase
XP_697087.4
640 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Agammaglobulinemia, type 1, X-linked.
XLA and isolated growth hormone deficiency.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
BTK (cl02465)
  BTK motif.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
SH2 (cl15255)
  Src homology 2 (SH2) domain.
SH3 (cl17036)
  Src Homology 3 domain superfamily.
PH-like (cl17171)
  Pleckstrin homology-like domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Btk includes H.sapiens BTK and R.norvegicus Btk.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (7 transcripts, 5 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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