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HomoloGene:109. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FANCC,  H.sapiens
Fanconi anemia, complementation group C
NP_001230672.1
558 aa
FANCC,  P.troglodytes
Fanconi anemia, complementation group C
XP_001151049.1
558 aa
FANCC,  M.mulatta
Fanconi anemia, complementation group C
XP_002800258.1
570 aa
FANCC,  C.lupus
Fanconi anemia, complementation group C
XP_848991.3
602 aa
FANCC,  B.taurus
Fanconi anemia, complementation group C
NP_776741.1
567 aa
Fancc,  M.musculus
Fanconi anemia, complementation group C
NP_001036138.1
558 aa
Fancc,  R.norvegicus
Fanconi anemia, complementation group C
NP_036689.2
557 aa
FANCC,  G.gallus
Fanconi anemia, complementation group C
NP_001006587.2
559 aa
fancc,  X.tropicalis
Fanconi anemia, complementation group C
XP_002935027.2
548 aa
fancc,  D.rerio
Fanconi anemia, complementation group C
NP_001035727.1
518 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Fanconi anemia, complementation group C.



Publications
Articles associated with genes and sequences of this homology group.

Fetal origins of hematopoietic failure in a murine model of Fanconi anemia.
Kamimae-Lanning AN, et al. Blood 121, 2008-12 (2013).
Impaired function of Fanconi anemia type C-deficient macrophages.
Liu Y, et al. J Leukoc Biol 91, 333-40 (2012).
Human FANCC is hypomorphic in murine Fancc-deficient cells.
Hays LE, et al. Blood 116, 2057-60 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Fanconi_C (pfam02106)
  Fanconi anaemia group C protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fancc includes H.sapiens FANCC and R.norvegicus Fancc.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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