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HomoloGene:2260. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SELP,  H.sapiens
selectin P (granule membrane protein 140kDa, antigen CD62)
NP_002996.2
830 aa
SELP,  P.troglodytes
selectin P (granule membrane protein 140kDa, antigen CD62)
XP_001137240.1
830 aa
SELP,  M.mulatta
selectin P (granule membrane protein 140kDa, antigen CD62)
XP_001094728.1
830 aa
SELP,  C.lupus
selectin P (granule membrane protein 140kDa, antigen CD62)
XP_537202.3
830 aa
Selp,  M.musculus
selectin, platelet
NP_035477.1
768 aa
Selp,  R.norvegicus
selectin P
NP_037246.1
768 aa
SELP,  G.gallus
selectin P (granule membrane protein 140kDa, antigen CD62)
XP_004943196.1
918 aa
selp,  X.tropicalis
selectin P (granule membrane protein 140kDa, antigen CD62)
XP_002933829.2
671 aa
selp,  D.rerio
selectin P
NP_001230252.1
868 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Atopy, susceptibility to.
Platelet alpha/delta storage pool deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Cytokine secretion from human monocytes potentiated by P-selectin-mediated cell adhesion.
Suzuki J, et al. Int Arch Allergy Immunol 160, 152-60 (2013).
The Thr715Pro variant impairs terminal glycosylation of P-selectin.
Subramanian H, et al. Thromb Haemost 108, 963-72 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
CCP (cl00043)
  SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.
CLECT (cl02432)
  C-type lectin (CTL)/C-type lectin-like (CTLD) domain.
EGF_CA (cl09941)
  Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Selp includes H.sapiens SELP and R.norvegicus Selp.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (6 transcripts, 5 species)

 

 

 

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