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HomoloGene:7399. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

LGALS1,  H.sapiens
lectin, galactoside-binding, soluble, 1
NP_002296.1
135 aa
LGALS1,  P.troglodytes
lectin, galactoside-binding, soluble, 1
XP_003953931.1
135 aa
LGALS1,  M.mulatta
lectin, galactoside-binding, soluble, 1
NP_001162098.1
135 aa
LGALS1,  C.lupus
lectin, galactoside-binding, soluble, 1
NP_001188417.1
135 aa
LGALS1,  B.taurus
lectin, galactoside-binding, soluble, 1
NP_786976.1
135 aa
Lgals1,  M.musculus
lectin, galactose binding, soluble 1
NP_032521.1
135 aa
Lgals1,  R.norvegicus
lectin, galactoside-binding, soluble, 1
NP_063969.1
135 aa
LGALS1,  G.gallus
lectin, galactoside-binding, soluble, 1
NP_996788.1
134 aa
LOC100485378,  X.tropicalis
galectin-1-like
XP_002934260.1
134 aa
lgals2a,  D.rerio
lectin, galactoside-binding, soluble, 2a
NP_998059.1
134 aa
lgals2b,  D.rerio
lectin, galactoside-binding, soluble, 2b
NP_956808.1
119 aa
lgals1l1,  D.rerio
lectin, galactoside-binding, soluble, 1 (galectin 1)-like 1
XP_005164019.1
134 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity.
Verschuere T, et al. Int J Cancer 134, 873-84 (2014).
Interfering with Gal-1-mediated angiogenesis contributes to the pathogenesis of preeclampsia.
Freitag N, et al. Proc Natl Acad Sci U S A 110, 11451-6 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
GLECT (cl00071)
  Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lgals1 includes H.sapiens LGALS1 and R.norvegicus Lgals1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (20 transcripts, 15 species)
Aves - birds (7 transcripts, 3 species)
Amniota - vertebrates (2 transcripts, 1 species)

Apicomplexa
Coccidia - apicomplexans (2 transcripts, 1 species)

 

 

 

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