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HomoloGene:7574. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TGIF1,  H.sapiens
TGFB-induced factor homeobox 1
NP_733796.2
401 aa
TGIF1,  P.troglodytes
TGFB-induced factor homeobox 1
NP_001009815.1
401 aa
TGIF1,  M.mulatta
TGFB-induced factor homeobox 1
XP_001083016.2
399 aa
TGIF1,  C.lupus
TGFB-induced factor homeobox 1
XP_547659.2
272 aa
TGIF1,  B.taurus
TGFB-induced factor homeobox 1
NP_001121971.1
252 aa
Tgif1,  M.musculus
TGFB-induced factor homeobox 1
NP_001157547.1
305 aa
Tgif1,  R.norvegicus
TGFB-induced factor homeobox 1
NP_001015020.1
287 aa
TGIF1,  G.gallus
TGFB-induced factor homeobox 1
NP_990710.1
269 aa
tgif1,  X.tropicalis
TGFB-induced factor homeobox 1
NP_989382.1
272 aa
tgif1,  D.rerio
transforming growth factor-beta-induced factor 1
NP_955861.1
273 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Holoprosencephaly-4.
Hypotrichosis simplex, contiguous gene syndrome with.



Publications
Articles associated with genes and sequences of this homology group.

Detection of TGIF1 homeobox gene in oral squamous cell carcinoma according to histologic grading.
Matizonkas-Antonio LF, et al. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 111, 218-24 (2011).
Tgif1 represses apolipoprotein gene expression in liver.
Melhuish TA, et al. J Cell Biochem 111, 380-90 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
homeodomain (cl00084)
  Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tgif1 includes H.sapiens TGIF1 and R.norvegicus Tgif1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (14 transcripts, 13 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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