Display Settings:

Format

Send to:

Choose Destination

Links from PubMed

HomoloGene:1327. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CAPNS1,  H.sapiens
calpain, small subunit 1
NP_001003962.1
268 aa
CAPNS1,  P.troglodytes
calpain, small subunit 1
XP_003953505.1
156 aa
LOC712561,  M.mulatta
calpain small subunit 1-like
XP_002808235.1
320 aa
CAPNS1,  C.lupus
calpain, small subunit 1
XP_853634.1
271 aa
CAPNS1,  B.taurus
calpain, small subunit 1
NP_776686.1
263 aa
Capns1,  M.musculus
calpain, small subunit 1
NP_033925.2
268 aa
Capns1,  R.norvegicus
calpain, small subunit 1
NP_058814.1
270 aa
LOC100912380,  R.norvegicus
calpain small subunit 1-like
XP_003748875.2
244 aa
LOC100911363,  R.norvegicus
calpain small subunit 1-like
XP_003748884.1
244 aa
capns2,  X.tropicalis
calpain, small subunit 2
NP_001016161.1
234 aa
capns1a,  D.rerio
calpain, small subunit 1 a
NP_001017899.2
216 aa
capns1b,  D.rerio
calpain, small subunit 1 b
NP_001103176.1
213 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Calpain protects the heart from hemodynamic stress.
Taneike M, et al. J Biol Chem 286, 32170-7 (2011).
DNA damage response links calpain to cellular senescence.
Demarchi F, et al. Cell Cycle 9, 755-60 (2010).
A new SNP in the 3'UTR region of the bovine calpain small subunit (CAPNS1) gene.
Juszczuk-Kubiak E, et al. Mol Biol Rep 37, 473-6 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EF_hand_6 (pfam13833)
  EF-hand domain pair.
FRQ1 (COG5126)
  Ca2+-binding protein (EF-Hand superfamily) [Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only].
EFh (cd00051)
  EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
EF-hand_8 (cl17302)
  EF-hand domain pair.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Capns1 includes H.sapiens CAPNS1 and R.norvegicus Capns1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (25 transcripts, 10 species)
Mammalia - mammals (17 transcripts, 13 species)
Amphibia - amphibians (5 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)

Arthropoda
Maxillopoda - crustaceans (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (1 transcript, 1 species)

 

 

 

Support Center