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HomoloGene:55450. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MPO,  H.sapiens
myeloperoxidase
NP_000241.1
745 aa
MPO,  P.troglodytes
myeloperoxidase
XP_001162602.2
745 aa
MPO,  M.mulatta
myeloperoxidase
XP_001103896.2
745 aa
MPO,  C.lupus
myeloperoxidase
XP_852445.2
718 aa
MPO,  B.taurus
myeloperoxidase
NP_001106769.1
719 aa
Mpo,  M.musculus
myeloperoxidase
NP_034954.2
718 aa
MPO,  G.gallus
myeloperoxidase
XP_004946465.1
949 aa
mpo,  X.tropicalis
myeloperoxidase
XP_002935236.2
724 aa
LOC100496213,  X.tropicalis
myeloperoxidase-like
XP_002933592.2
716 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Alzheimer disease, susceptibility to.
Myeloperoxidase deficiency.



Publications
Articles associated with genes and sequences of this homology group.

Inactivation of human myeloperoxidase by hydrogen peroxide.
Paumann-Page M, et al. Arch Biochem Biophys 539, 51-62 (2013).
Myeloperoxidase G463A polymorphism and risk of lung cancer.
Li J, et al. Tumour Biol 35, 821-9 (2014).
Association of myeloperoxidase with ovarian cancer.
Castillo-Tong DC, et al. Tumour Biol 35, 141-8 (2014).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
An_peroxidase_like (cl14561)
  Animal heme peroxidases and related proteins.
An_peroxidase_like (cl14561)
  Animal heme peroxidases and related proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mpo includes H.sapiens MPO and R.norvegicus Mpo.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (5 transcripts, 5 species)
Amphibia - amphibians (3 transcripts, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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