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HomoloGene:55480. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ALDH2,  H.sapiens
aldehyde dehydrogenase 2 family (mitochondrial)
NP_000681.2
517 aa
ALDH2,  P.troglodytes
aldehyde dehydrogenase 2 family (mitochondrial)
XP_509379.3
462 aa
ALDH2,  M.mulatta
aldehyde dehydrogenase, mitochondrial-like
XP_002808038.1
517 aa
ALDH2,  C.lupus
aldehyde dehydrogenase 2 family (mitochondrial)
XP_853628.1
521 aa
ALDH2,  B.taurus
aldehyde dehydrogenase 2 family (mitochondrial)
NP_001068835.1
520 aa
Aldh2,  M.musculus
aldehyde dehydrogenase 2, mitochondrial
NP_033786.1
519 aa
Aldh2,  R.norvegicus
aldehyde dehydrogenase 2 family (mitochondrial)
NP_115792.1
519 aa
ALDH2,  G.gallus
aldehyde dehydrogenase 2 family (mitochondrial)
XP_415171.3
519 aa
aldh2,  X.tropicalis
aldehyde dehydrogenase 2 family (mitochondrial)
NP_001004907.1
521 aa
aldh2.1,  D.rerio
aldehyde dehydrogenase 2, tandem duplicate 1
NP_956784.1
516 aa
aldh2l,  D.rerio
aldehyde dehydrogenase 2, like
XP_002662252.1
516 aa
aldh2.2,  D.rerio
aldehyde dehydrogenase 2, tandem duplicate 2
NP_998466.2
516 aa
Aldh,  D.melanogaster
Aldehyde dehydrogenase
NP_609285.1
520 aa
AgaP_AGAP003652,  A.gambiae
AgaP_AGAP003652
XP_313425.3
515 aa
alh-1,  C.elegans
alh-1
NP_498081.2
510 aa
alh-2,  C.elegans
alh-2
NP_503467.2
514 aa
ALD5,  S.cerevisiae
ALD5
NP_010996.2
520 aa
KLLA0C07777g,  K.lactis
KLLA0C07777g
XP_452546.1
514 aa
AGOS_ACL044W,  E.gossypii
AGOS_ACL044W
NP_983360.1
513 aa
SPAC9E9.09c,  S.pombe
SPAC9E9.09c
NP_594582.1
503 aa
MGG_03900,  M.oryzae
MGG_03900
XP_003719976.1
496 aa
NCU03415,  N.crassa
NCU03415
XP_956862.1
494 aa
ALDH2B4,  A.thaliana
ALDH2B4
NP_190383.1
538 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
?Fetal alcohol syndrome.
Alcohol intolerance, acute.



Publications
Articles associated with genes and sequences of this homology group.

Targeting aldehyde dehydrogenase 2: new therapeutic opportunities.
Chen CH, et al. Physiol Rev 94, 1-34 (2014).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PLN02466 (PLN02466)
  aldehyde dehydrogenase family 2 member.
ALDH-SF (cl11961)
  NAD(P)+-dependent aldehyde dehydrogenase superfamily.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Aldh2 includes H.sapiens ALDH2 and R.norvegicus Aldh2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (24 transcripts, 11 species)
Mammalia - mammals (23 transcripts, 14 species)
Aves - birds (4 transcripts, 3 species)
Amphibia - amphibians (4 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (15 transcripts, 12 species)
Arachnida - arachnids (8 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (5 transcripts, 2 species)
Turbellaria - flatworms (2 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Annelida
Hirudinida - segmented worms (2 transcripts, 1 species)
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (59 transcripts, 32 species)
Liliopsida - monocots (6 transcripts, 3 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)
Bryopsida - mosses (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

 

 

 

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