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HomoloGene:543. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ACHE,  H.sapiens
acetylcholinesterase (Yt blood group)
NP_000656.1
614 aa
ACHE,  P.troglodytes
acetylcholinesterase
XP_003318708.1
614 aa
ACHE,  M.mulatta
acetylcholinesterase
NP_001121560.1
614 aa
ACHE,  C.lupus
acetylcholinesterase
XP_005621080.1
611 aa
ACHE,  B.taurus
acetylcholinesterase
NP_001069688.1
613 aa
Ache,  M.musculus
acetylcholinesterase
NP_033729.1
614 aa
Ache,  R.norvegicus
acetylcholinesterase
NP_742006.1
614 aa
ACHE,  G.gallus
acetylcholinesterase
NP_990749.1
767 aa
LOC100490673,  X.tropicalis
acetylcholinesterase-like
XP_002940088.1
600 aa
ache,  D.rerio
acetylcholinesterase
NP_571921.1
634 aa
ACES_ANOGA,  A.gambiae
ACES_ANOGA
XP_321792.2
737 aa
ace-1,  C.elegans
ace-1
NP_510660.1
620 aa
MGG_02130,  M.oryzae
MGG_02130
XP_003708907.1
567 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Blood group, Yt system.



Publications
Articles associated with genes and sequences of this homology group.

Cholinergic innervation of human mesenteric lymphatic vessels.
D'Andrea V, et al. Folia Morphol (Warsz) 72, 322-7 (2013).
Acetylcholinesterase activity and neurodevelopment in boys and girls.
Suarez-Lopez JR, et al. Pediatrics 132, e1649-58 (2013).
Free energy landscape for the binding process of Huperzine A to acetylcholinesterase.
Bai F, et al. Proc Natl Acad Sci U S A 110, 4273-8 (2013).
Polyproline tetramer organizing peptides in fetal bovine serum acetylcholinesterase.
Biberoglu K, et al. Biochim Biophys Acta 1834, 745-53 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AChE_tetra (pfam08674)
  Acetylcholinesterase tetramerization domain.
Esterase_lipase (cl12031)
  Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These ...
COesterase (pfam00135)
  Carboxylesterase family.
Aes (COG0657)
  Esterase/lipase [Lipid metabolism].
Esterase_lipase (cl19094)
  Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ache includes H.sapiens ACHE and R.norvegicus Ache.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Cephalochordata - lancelets (4 transcripts, 1 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 7 species)
Arachnida - arachnids (8 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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