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HomoloGene:33482. Gene conserved in Tetrapoda Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FOXP2,  H.sapiens
forkhead box P2
NP_683696.2
740 aa
FOXP2,  P.troglodytes
forkhead box P2
NP_001009020.1
716 aa
LOC482413,  C.lupus
forkhead box protein P2-like
XP_005628804.1
737 aa
LOC505502,  B.taurus
uncharacterized LOC505502
NP_001192498.1
745 aa
Foxp2,  R.norvegicus
forkhead box P2
NP_001258033.1
710 aa
foxp2,  X.tropicalis
forkhead box P2
NP_001093722.1
738 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Speech-language disorder-1.



Publications
Articles associated with genes and sequences of this homology group.

Foxp2 mutations impair auditory-motor association learning.
Kurt S, et al. PLoS One 7, e33130 (2012).
Imaging genetics of FOXP2 in dyslexia.
Wilcke A, et al. Eur J Hum Genet 20, 224-9 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FH (cl00061)
  Forkhead (FH), also known as a "winged helix". FH is named for the Drosophila fork head protein, a transcription factor which promotes terminal rather than segmental development. This family of transcription factor domains, which bind to B-DNA ...



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (10 transcripts, 10 species)
Actinopterygii - bony fishes (8 transcripts, 6 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Streptophyta
Coniferopsida - conifers (1 transcript, 1 species)

 

 

 

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