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HomoloGene:124071. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DNMT1,  H.sapiens
DNA (cytosine-5-)-methyltransferase 1
NP_001124295.1
1632 aa
DNMT1,  P.troglodytes
DNA (cytosine-5-)-methyltransferase 1
XP_512361.3
1632 aa
DNMT1,  M.mulatta
DNA (cytosine-5-)-methyltransferase 1
XP_001104704.2
1280 aa
DNMT1,  C.lupus
DNA (cytosine-5-)-methyltransferase 1
XP_533919.4
1645 aa
DNMT1,  B.taurus
DNA (cytosine-5-)-methyltransferase 1
NP_872592.2
1611 aa
Dnmt1,  M.musculus
DNA methyltransferase (cytosine-5) 1
NP_001186360.2
1620 aa
Dnmt1,  R.norvegicus
DNA (cytosine-5-)-methyltransferase 1
NP_445806.3
1621 aa
DNMT1,  G.gallus
DNA (cytosine-5-)-methyltransferase 1
NP_996835.1
1537 aa
dnmt1,  X.tropicalis
DNA (cytosine-5-)-methyltransferase 1
XP_002934384.1
1492 aa
dnmt1,  D.rerio
DNA (cytosine-5-)-methyltransferase 1
NP_571264.1
1499 aa
DMT2,  A.thaliana
DMT2
NP_193150.1
1519 aa
AT4G08990,  A.thaliana
AT4G08990
NP_192638.1
1512 aa
MEE57,  A.thaliana
MEE57
NP_193097.1
1404 aa
MET1,  A.thaliana
MET1
NP_199727.1
1534 aa
Os03g0798300,  O.sativa
Os03g0798300
NP_001051569.1
413 aa
Os07g0182900,  O.sativa
Os07g0182900
NP_001059052.1
445 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
???.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-CXXC (pfam02008)
  CXXC zinc finger domain.
AdoMet_MTases (cl16911)
  S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
DMAP_binding (pfam06464)
  DMAP1-binding Domain.
DNMT1-RFD (pfam12047)
  Cytosine specific DNA methyltransferase replication foci domain.
PRK13863 (PRK13863)
  type IV secretion system T-DNA border endonuclease VirD2; Provisional.
zf-CXXC (pfam02008)
  CXXC zinc finger domain.
DMAP_binding (pfam06464)
  DMAP1-binding Domain.
DNMT1-RFD (pfam12047)
  Cytosine specific DNA methyltransferase replication foci domain.
BAH (cl02608)
  BAH, or Bromo Adjacent Homology domain (also called ELM1 and BAM for Bromo Adjacent Motif). BAH domains have first been described as domains found in the polybromo protein and Yeast Rsc1/Rsc2 (Remodeling of the Structure of Chromatin). They also occur in ...
Cyt_C5_DNA_methylase (cl19095)
  Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dnmt1 includes H.sapiens DNMT1 and R.norvegicus Dnmt1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (19 transcripts, 13 species)
Actinopterygii - bony fishes (18 transcripts, 11 species)
Ascidiacea - tunicates (4 transcripts, 2 species)
Aves - birds (3 transcripts, 1 species)
Amphibia - amphibians (3 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 4 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (5 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (29 transcripts, 21 species)
Liliopsida - monocots (9 transcripts, 7 species)
Coniferopsida - conifers (2 transcripts, 2 species)

 

 

 

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