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HomoloGene:128610. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CCDC114,  H.sapiens
coiled-coil domain containing 114
NP_653178.3
670 aa
CCDC114,  P.troglodytes
coiled-coil domain containing 114
XP_003316531.2
674 aa
LOC717829,  M.mulatta
coiled-coil domain-containing protein 114-like
XP_002801395.1
623 aa
CCDC114,  C.lupus
coiled-coil domain containing 114
XP_005616412.1
704 aa
CCDC114,  B.taurus
coiled-coil domain containing 114
XP_003587326.2
692 aa
Ccdc114,  M.musculus
coiled-coil domain containing 114
NP_001028415.1
658 aa
Ccdc114,  R.norvegicus
coiled-coil domain containing 114
NP_001119749.1
694 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
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Publications
Articles associated with genes and sequences of this homology group.

Loss-of-function mutations in CCDC114 cause primary ciliary dyskinesia.
Wu DH & Singaraja RR. Clin Genet 83, 526-7 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Smc (COG1196)
  Chromosome segregation ATPases [Cell division and chromosome partitioning].
COG5293 (COG5293)
  Predicted ATPase [General function prediction only].
SMC_prok_B (TIGR02168)
  chromosome segregation protein SMC, common bacterial type.
PRK12704 (PRK12704)
  phosphodiesterase; Provisional.
DUF342 (cl19219)
  Protein of unknown function (DUF342).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ccdc114 includes H.sapiens CCDC114 and R.norvegicus Ccdc114.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (4 transcripts, 4 species)

 

 

 

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