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HomoloGene:21193. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DNAJA2,  H.sapiens
DnaJ (Hsp40) homolog, subfamily A, member 2
NP_005871.1
412 aa
DNAJA2,  P.troglodytes
DnaJ (Hsp40) homolog, subfamily A, member 2
XP_528644.3
412 aa
DNAJA2,  M.mulatta
DnaJ (Hsp40) homolog, subfamily A, member 2
XP_001082094.1
412 aa
DNAJA2,  C.lupus
DnaJ (Hsp40) homolog, subfamily A, member 2
XP_535319.4
412 aa
DNAJA2,  B.taurus
DnaJ (Hsp40) homolog, subfamily A, member 2
NP_001035581.1
412 aa
Dnaja2,  M.musculus
DnaJ (Hsp40) homolog, subfamily A, member 2
NP_062768.1
412 aa
Dnaja2,  R.norvegicus
DnaJ (Hsp40) homolog, subfamily A, member 2
NP_114468.2
412 aa
DNAJA2,  G.gallus
DnaJ (Hsp40) homolog, subfamily A, member 2
NP_001005841.1
411 aa
dnaja2,  X.tropicalis
DnaJ (Hsp40) homolog, subfamily A, member 2
NP_001004807.1
410 aa
dnaja2,  D.rerio
DnaJ (Hsp40) homolog, subfamily A, member 2
NP_998658.1
412 aa
dnj-19,  C.elegans
dnj-19
NP_504452.1
439 aa
YDJ1,  S.cerevisiae
YDJ1
NP_014335.1
409 aa
KLLA0F03333g,  K.lactis
KLLA0F03333g
XP_455231.1
409 aa
AGOS_ADL257C,  E.gossypii
AGOS_ADL257C
NP_983839.1
410 aa
mas5,  S.pombe
mas5
NP_595428.1
407 aa
MGG_04462,  M.oryzae
MGG_04462
XP_003710999.1
417 aa
NCU07414,  N.crassa
NCU07414
XP_958415.1
414 aa
ATJ3,  A.thaliana
ATJ3
NP_189997.1
420 aa
J2,  A.thaliana
J2
NP_568412.1
419 aa
Os03g0648400,  O.sativa
Os03g0648400
NP_001050779.1
417 aa
Os03g0787300,  O.sativa
Os03g0787300
NP_001051497.1
417 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Identification of a consensus motif in substrates bound by a Type I Hsp40.
Kota P, et al. Proc Natl Acad Sci U S A 106, 11073-8 (2009).
MAS5, a yeast homolog of DnaJ involved in mitochondrial protein import.
Atencio DP & Yaffe MP. Mol Cell Biol 12, 283-91 (1992).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DnaJ_C (cd10747)
  C-terminal substrate binding domain of DnaJ and HSP40.
DnaJ_C (cl03262)
  C-terminal substrate binding domain of DnaJ and HSP40.
DnaJ (cl02542)
  DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
DnaJ_zf (cl19048)
  Zinc finger domain of DnaJ and HSP40.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Dnaja2 includes H.sapiens DNAJA2 and R.norvegicus Dnaja2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (106 transcripts, 35 species)
Liliopsida - monocots (34 transcripts, 9 species)
Coniferopsida - conifers (9 transcripts, 3 species)
Bryopsida - mosses (5 transcripts, 1 species)
Isoetopsida - club-mosses (5 transcripts, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Chordata
Actinopterygii - bony fishes (25 transcripts, 10 species)
Mammalia - mammals (20 transcripts, 15 species)
Amphibia - amphibians (4 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (7 transcripts, 7 species)
Arachnida - arachnids (2 transcripts, 2 species)
Malacostraca - crustaceans (2 transcripts, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (4 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (3 transcripts, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (3 transcripts, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (3 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

 

 

 

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