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HomoloGene:4664. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RNASEH2A,  H.sapiens
ribonuclease H2, subunit A
NP_006388.2
299 aa
RNASEH2A,  P.troglodytes
ribonuclease H2, subunit A
XP_512415.1
299 aa
RNASEH2A,  M.mulatta
ribonuclease H2, subunit A
XP_001109423.1
300 aa
RNASEH2A,  C.lupus
ribonuclease H2, subunit A
XP_003639769.1
299 aa
RNASEH2A,  B.taurus
ribonuclease H2, subunit A
NP_001033623.1
299 aa
Rnaseh2a,  M.musculus
ribonuclease H2, large subunit
NP_081463.1
301 aa
Rnaseh2a,  R.norvegicus
ribonuclease H2, subunit A
NP_001013252.1
301 aa
rnaseh2a,  X.tropicalis
ribonuclease H2, subunit A
NP_989146.1
301 aa
rnaseh2a,  D.rerio
ribonuclease H2, subunit A
NP_956520.2
307 aa
CG13690,  D.melanogaster
CG13690
NP_608521.1
347 aa
AgaP_AGAP007741,  A.gambiae
AgaP_AGAP007741
XP_317779.3
342 aa
rnh-2,  C.elegans
rnh-2
NP_495796.1
297 aa
RNH201,  S.cerevisiae
RNH201
NP_014327.1
307 aa
KLLA0F04774g,  K.lactis
KLLA0F04774g
XP_455296.1
304 aa
AGOS_AER363W,  E.gossypii
AGOS_AER363W
NP_985219.2
304 aa
rnh201,  S.pombe
rnh201
NP_593684.1
326 aa
MGG_06959,  M.oryzae
MGG_06959
XP_003709705.1
355 aa
NCU09608,  N.crassa
NCU09608
XP_963372.2
381 aa
AT2G25100,  A.thaliana
AT2G25100
NP_565584.1
296 aa
Os11g0153900,  O.sativa
Os11g0153900
NP_001065783.1
298 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Aicardi-Goutieres syndrome 4.



Publications
Articles associated with genes and sequences of this homology group.

Transcriptional responses to loss of RNase H2 in Saccharomyces cerevisiae.
Arana ME, et al. DNA Repair (Amst) 11, 933-41 (2012).
RNase H2-initiated ribonucleotide excision repair.
Sparks JL, et al. Mol Cell 47, 980-6 (2012).
Proofreading of ribonucleotides inserted into DNA by yeast DNA polymerase ɛ.
Williams JS, et al. DNA Repair (Amst) 11, 649-56 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RNase_HII_eukaryota_like (cd07181)
  Mammalian RNase HII is functional when it forms a complex with two other accessory protein.
RNase_H (cl14782)
  RNase H is an endonuclease that cleaves the RNA strand of an RNA/DNA hybrid in a sequence non-specific manner.
RNase_H_like (cl14782)
  Ribonuclease H-like superfamily, including RNase H, HI, HII, HIII, and RNase-like domain IV of spliceosomal protein Prp8.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rnaseh2a includes H.sapiens RNASEH2A and R.norvegicus Rnaseh2a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (8 transcripts, 8 species)
Ascidiacea - tunicates (3 transcripts, 3 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (6 transcripts, 6 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (24 transcripts, 22 species)
Liliopsida - monocots (7 transcripts, 5 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Bryopsida - mosses (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

 

 

 

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