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HomoloGene:55492. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HTR2B,  H.sapiens
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
NP_000858.3
481 aa
HTR2B,  P.troglodytes
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
XP_001144172.1
481 aa
HTR2B,  M.mulatta
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
XP_001113095.1
481 aa
HTR2B,  C.lupus
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
NP_001019804.1
434 aa
HTR2B,  B.taurus
5-hydroxytryptamine (serotonin) receptor 2B
NP_001192377.1
480 aa
Htr2b,  M.musculus
5-hydroxytryptamine (serotonin) receptor 2B
NP_032337.2
479 aa
Htr2b,  R.norvegicus
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
NP_058946.1
479 aa
HTR2B,  G.gallus
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
XP_004943419.1
462 aa
htr2b,  X.tropicalis
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
XP_004914439.1
478 aa
htr2b,  D.rerio
5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
NP_001038208.1
443 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Role of peripheral and spinal 5-HT2B receptors in formalin-induced nociception.
Cervantes-DurĂ¡n C, et al. Pharmacol Biochem Behav 102, 30-5 (2012).
Enamel alterations in serotonin 2B receptor knockout mice.
Harichane Y, et al. Eur J Oral Sci 119 Suppl 1, 177-84 (2011).
Implication of 5-HT(2B) receptors in the serotonin syndrome.
Diaz SL & Maroteaux L. Neuropharmacology 61, 495-502 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Htr2b includes H.sapiens HTR2B and R.norvegicus Htr2b.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 8 species)
Amphibia - amphibians (2 transcripts, 2 species)
Actinopterygii - bony fishes (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

 

 

 

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