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HomoloGene:8666. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

STAU2,  H.sapiens
staufen double-stranded RNA binding protein 2
NP_001157852.1
570 aa
STAU2,  P.troglodytes
staufen, RNA binding protein, homolog 2 (Drosophila)
XP_001165116.1
570 aa
STAU2,  M.mulatta
staufen, RNA binding protein, homolog 2 (Drosophila)
XP_001084686.2
570 aa
STAU2,  C.lupus
staufen double-stranded RNA binding protein 2
XP_005638102.1
624 aa
STAU2,  B.taurus
staufen, RNA binding protein, homolog 2 (Drosophila)
NP_001096783.1
538 aa
Stau2,  M.musculus
staufen (RNA binding protein) homolog 2 (Drosophila)
NP_079579.2
570 aa
Stau2,  R.norvegicus
staufen double-stranded RNA binding protein 2
NP_001007150.1
571 aa
STAU2,  G.gallus
staufen, RNA binding protein, homolog 2 (Drosophila)
NP_001026112.1
472 aa
stau2,  X.tropicalis
staufen double-stranded RNA binding protein 2
NP_001011376.2
706 aa
stau2,  D.rerio
staufen, RNA binding protein, homolog 2 (Drosophila)
NP_957219.2
678 aa
AgaP_AGAP007478,  A.gambiae
AgaP_AGAP007478
XP_308394.4
1149 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The double-stranded RNA-binding protein Staufen 2 regulates eye size.
Cockburn DM, et al. Mol Cell Neurosci 51, 101-11 (2012).
Genome wide identification of Staufen2-bound mRNAs in embryonic rat brains.
Maher-Laporte M & DesGroseillers L. BMB Rep 43, 344-8 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DSRM (cl00054)
  Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Stau2 includes H.sapiens STAU2 and R.norvegicus Stau2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (22 transcripts, 16 species)
Actinopterygii - bony fishes (8 transcripts, 8 species)
Aves - birds (3 transcripts, 2 species)
Amphibia - amphibians (3 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 7 species)
Arachnida - arachnids (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (4 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (3 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

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