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HomoloGene:35. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ATP7A,  H.sapiens
ATPase, Cu++ transporting, alpha polypeptide
NP_000043.4
1500 aa
ATP7A,  P.troglodytes
ATPase, Cu++ transporting, alpha polypeptide
XP_003954073.1
1486 aa
ATP7A,  C.lupus
ATPase, Cu++ transporting, alpha polypeptide
XP_005641578.1
1499 aa
ATP7A,  B.taurus
ATPase, Cu++ transporting, alpha polypeptide
NP_001179781.1
1500 aa
Atp7a,  M.musculus
ATPase, Cu++ transporting, alpha polypeptide
NP_001103227.1
1492 aa
Atp7a,  R.norvegicus
ATPase, Cu++ transporting, alpha polypeptide
NP_434690.1
1492 aa
ATP7A,  G.gallus
ATPase, Cu++ transporting, alpha polypeptide
XP_004940860.1
1494 aa
atp7a,  D.rerio
ATPase, Cu++ transporting, alpha polypeptide
NP_001036185.1
1482 aa
ATP7,  D.melanogaster
ATP7
NP_001259466.1
1254 aa
AgaP_AGAP011754,  A.gambiae
AgaP_AGAP011754
XP_552490.3
1167 aa
cua-1,  C.elegans
cua-1
NP_001255202.1
1238 aa
CCC2,  S.cerevisiae
CCC2
NP_010556.1
1004 aa
KLLA0F07447g,  K.lactis
KLLA0F07447g
XP_455418.1
975 aa
ccc2,  S.pombe
ccc2
NP_595829.1
904 aa
MGG_03724,  M.oryzae
MGG_03724
XP_003716156.1
1190 aa
NCU08341,  N.crassa
NCU08341
XP_965244.1
1181 aa
HMA5,  A.thaliana
HMA5
NP_176533.1
995 aa
Os04g0556000,  O.sativa
Os04g0556000
NP_001053522.2
849 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cutis laxa, neonatal.
Occipital horn syndrome.
Menkes disease.



Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HAD_like (cd01427)
  Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others, ...
HAD_like (cl11391)
  Haloacid Dehalogenase-like Hydrolases.
E1-E2_ATPase (pfam00122)
  E1-E2 ATPase.
COG4087 (COG4087)
  Soluble P-type ATPase [General function prediction only].
E1-E2_ATPase (pfam00122)
  E1-E2 ATPase.
HMA (cl00207)
  Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain ...
HAD (cl19137)
  haloacid dehalogenase-like hydrolase.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atp7a includes H.sapiens ATP7A and R.norvegicus Atp7a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (44 transcripts, 23 species)
Liliopsida - monocots (18 transcripts, 8 species)
Coniferopsida - conifers (6 transcripts, 2 species)
Bryopsida - mosses (1 transcript, 1 species)

Chordata
Mammalia - mammals (12 transcripts, 9 species)
Actinopterygii - bony fishes (8 transcripts, 6 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (4 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (3 transcripts, 1 species)
Pythiales - oomycetes (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (5 transcripts, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

 

 

 

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