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HomoloGene:6028. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

WDR45B,  H.sapiens
WD repeat domain 45B
NP_062559.2
344 aa
WDR45L,  P.troglodytes
WDR45-like
XP_001168446.2
344 aa
WDR45B,  C.lupus
WD repeat domain 45B
XP_537936.4
335 aa
WDR45L,  B.taurus
WDR45-like
NP_001068715.1
344 aa
Wdr45b,  M.musculus
WD repeat domain 45B
NP_080069.2
344 aa
Wdr45b,  R.norvegicus
WD repeat domain 45B
NP_001034676.1
344 aa
WDR45L,  G.gallus
WDR45-like
NP_001007845.1
344 aa
wdr45b,  X.tropicalis
WD repeat domain 45B
NP_001008184.1
344 aa
wdr45l,  D.rerio
wdr45 like
NP_956534.1
344 aa
CG11975,  D.melanogaster
CG11975
NP_001262394.1
340 aa
AgaP_AGAP012792,  A.gambiae
AgaP_AGAP012792
XP_560966.5
348 aa
ATG18C,  A.thaliana
ATG18C
NP_973650.1
393 aa
ATG18D,  A.thaliana
ATG18D
NP_191203.2
391 aa
Os01g0168500,  O.sativa
Os01g0168500
NP_001042130.1
417 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

PtdIns-specific MPR pathway association of a novel WD40 repeat protein, WIPI49.
Jeffries TR, et al. Mol Biol Cell 15, 2652-63 (2004).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
COG2319 (COG2319)
  FOG: WD40 repeat [General function prediction only].
WD40 (cd00200)
  WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
WD40 (cl02567)
  WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Wdr45b includes H.sapiens WDR45B.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (33 transcripts, 25 species)
Liliopsida - monocots (13 transcripts, 8 species)
Coniferopsida - conifers (10 transcripts, 3 species)
Bryopsida - mosses (4 transcripts, 1 species)
Isoetopsida - club-mosses (2 transcripts, 1 species)

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (7 transcripts, 7 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Arthropoda
Insecta - insects (11 transcripts, 10 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Ascomycota
Eurotiomycetes - ascomycetes (2 transcripts, 1 species)
Sordariomycetes - ascomycetes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 2 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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