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HomoloGene:2192. Gene conserved in Tetrapoda Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

RGS2,  H.sapiens
regulator of G-protein signaling 2, 24kDa
211 aa
RGS2,  P.troglodytes
regulator of G-protein signaling 2, 24kDa
211 aa
RGS2,  M.mulatta
regulator of G-protein signaling 2, 24kDa
211 aa
RGS2,  C.lupus
regulator of G-protein signaling 2, 24kDa
300 aa
Rgs2,  M.musculus
regulator of G-protein signaling 2
211 aa
Rgs2,  R.norvegicus
regulator of G-protein signaling 2
211 aa
RGS2,  G.gallus
regulator of G-protein signaling 2, 24kDa
225 aa
rgs2,  X.tropicalis
regulator of G-protein signaling 2, 24kDa
217 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Genetic association study between RGS2 and anxiety-related phenotypes.
Hettema JM, et al. Psychiatr Genet 23, 92 (2013).
RGS2 is a component of the cellular stress response.
Nguyen CH, et al. Biochem Biophys Res Commun 426, 129-34 (2012).
Cardiotonic steroids stabilize regulator of G protein signaling 2 protein levels.
Sjögren B, et al. Mol Pharmacol 82, 500-9 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RGS (cl02565)
  Regulator of G protein signaling (RGS) domain superfamily.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rgs2 includes H.sapiens RGS2 and R.norvegicus Rgs2.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (10 transcripts, 10 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Trematoda - flatworms (1 transcript, 1 species)




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