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HomoloGene:31092. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MYC,  H.sapiens
v-myc avian myelocytomatosis viral oncogene homolog
NP_002458.2
454 aa
MYC,  P.troglodytes
v-myc myelocytomatosis viral oncogene homolog (avian)
NP_001136266.1
454 aa
MYC,  M.mulatta
v-myc myelocytomatosis viral oncogene homolog (avian)
NP_001136345.1
439 aa
MYC,  C.lupus
v-myc myelocytomatosis viral oncogene homolog (avian)
NP_001003246.2
452 aa
MYC,  B.taurus
v-myc myelocytomatosis viral oncogene homolog (avian)
NP_001039539.1
439 aa
Myc,  M.musculus
myelocytomatosis oncogene
NP_034979.3
454 aa
Myc,  R.norvegicus
myelocytomatosis oncogene
NP_036735.2
453 aa
MYC,  G.gallus
v-myc myelocytomatosis viral oncogene homolog
NP_001026123.1
416 aa
MGC76254,  X.tropicalis
uncharacterized protein MGC76254
NP_989390.1
418 aa
myca,  D.rerio
myelocytomatosis oncogene a
NP_571487.2
419 aa
mycb,  D.rerio
myelocytomatosis oncogene b
NP_956466.1
396 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Burkitt lymphoma.



Publications
Articles associated with genes and sequences of this homology group.

Myc-driven endogenous cell competition in the early mammalian embryo.
Clavería C, et al. Nature 500, 39-44 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Myc-LZ (pfam02344)
  Myc leucine zipper domain.
Myc_N (pfam01056)
  Myc amino-terminal region.
Myc_N (pfam01056)
  Myc amino-terminal region.
HLH (cl00081)
  Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Myc includes H.sapiens MYC and R.norvegicus Myc.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (15 transcripts, 9 species)
Mammalia - mammals (12 transcripts, 12 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)

 

 

 

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