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HomoloGene:110676. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HMGB1,  H.sapiens
high mobility group box 1
NP_002119.1
215 aa
HMGB1,  P.troglodytes
high mobility group box 1
XP_509611.1
215 aa
HMGB1,  M.mulatta
high mobility group box 1
XP_001100203.1
215 aa
HMGB1,  C.lupus
high mobility group box 1
NP_001002937.1
215 aa
HMGB1,  B.taurus
high mobility group box 1
NP_788785.1
215 aa
LOC685520,  R.norvegicus
similar to High mobility group protein 1 (HMG-1) (High mobility group protein B1) (Amphoterin) (Heparin-binding protein p30)
XP_003749961.1
215 aa
HMGB1,  G.gallus
high mobility group box 1
NP_990233.1
215 aa
hmgb1a,  D.rerio
high-mobility group box 1a
NP_955849.2
205 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

[Effect of HMGB1 on invasion and migration of human hepatoma cell line HepG2 and its mechanism].
Wang C, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 29, 1159-62 (2013).
Are HMGB1 protein expression and secretion markers of upper airways inflammatory diseases?
Bellussi LM, et al. J Biol Regul Homeost Agents 27, 791-804 (2013).
HMGB1 gene polymorphisms in patients with chronic hepatitis B virus infection.
Deng CQ, et al. World J Gastroenterol 19, 5144-9 (2013).
Increased expression of high-mobility group protein B1 in chronic rhinosinusitis.
Hong SM, et al. Am J Rhinol Allergy 27, 278-82 (2013).
Endogenous HMGB1 is required in endotoxin tolerance.
Li S, et al. J Surg Res 185, 319-28 (2013).
HMGB1 in cancer: good, bad, or both?
Kang R, et al. Clin Cancer Res 19, 4046-57 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
HMG-box (cl00082)
  High Mobility Group (HMG)-box is found in a variety of eukaryotic chromosomal proteins and transcription factors. HMGs bind to the minor groove of DNA and have been classified by DNA binding preferences. Two phylogenically distinct groups of Class I ...



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (57 transcripts, 18 species)
Actinopterygii - bony fishes (32 transcripts, 10 species)
Hyperoartia - vertebrates (5 transcripts, 1 species)
Amniota - vertebrates (2 transcripts, 1 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)

Arthropoda
Insecta - insects (13 transcripts, 12 species)
Arachnida - arachnids (3 transcripts, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Liliopsida - monocots (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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