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HomoloGene:3566. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ATG5,  H.sapiens
autophagy related 5
NP_001273035.1
275 aa
ATG5,  P.troglodytes
autophagy related 5
XP_518659.1
275 aa
ATG5,  M.mulatta
autophagy related 5
XP_001088076.1
275 aa
ATG5,  C.lupus
autophagy related 5
XP_854294.1
275 aa
ATG5,  B.taurus
ATG5 autophagy related 5 homolog (S. cerevisiae)
NP_001029751.2
275 aa
Atg5,  M.musculus
autophagy related 5
NP_444299.1
275 aa
ATG5,  G.gallus
autophagy related 5
NP_001006409.1
275 aa
atg5,  X.tropicalis
autophagy related 5
NP_001016445.1
233 aa
atg5,  D.rerio
ATG5 autophagy related 5 homolog (S. cerevisiae)
NP_001009914.2
275 aa
Atg5,  D.melanogaster
Autophagy-specific gene 5
NP_572390.1
269 aa
AgaP_AGAP010939,  A.gambiae
AgaP_AGAP010939
XP_309756.4
265 aa
atg-5,  C.elegans
atg-5
NP_490885.3
275 aa
APG5,  A.thaliana
APG5
NP_197231.1
337 aa
Os02g0117800,  O.sativa
Os02g0117800
NP_001045690.1
380 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

ATG5 regulates plasma cell differentiation.
Conway KL, et al. Autophagy 9, 528-37 (2013).
Down-regulated expression of ATG5 in colorectal cancer.
Cho DH, et al. Anticancer Res 32, 4091-6 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
APG5 (pfam04106)
  Autophagy protein Apg5.
APG5 (pfam04106)
  Autophagy protein Apg5.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Atg5 includes H.sapiens ATG5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 14 species)
Actinopterygii - bony fishes (7 transcripts, 7 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (11 transcripts, 11 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (19 transcripts, 19 species)
Liliopsida - monocots (5 transcripts, 5 species)
Coniferopsida - conifers (2 transcripts, 2 species)

Ascomycota
Pezizomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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