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HomoloGene:69317. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NLGN2,  H.sapiens
neuroligin 2
NP_065846.1
835 aa
NLGN2,  P.troglodytes
neuroligin 2
XP_523830.3
781 aa
NLGN2,  M.mulatta
neuroligin 2
XP_001108431.2
836 aa
NLGN2,  C.lupus
neuroligin 2
XP_849499.2
835 aa
NLGN2,  B.taurus
neuroligin 2
NP_001178171.1
835 aa
Nlgn2,  M.musculus
neuroligin 2
NP_942562.2
836 aa
Nlgn2,  R.norvegicus
neuroligin 2
NP_446444.1
836 aa
nlgn2,  X.tropicalis
neuroligin 2
XP_002944465.2
642 aa
nlgn2a,  D.rerio
neuroligin 2a
NP_001159808.1
860 aa
nlgn2b,  D.rerio
neuroligin 2b
NP_001159801.1
810 aa
CG34127,  D.melanogaster
CG34127
NP_001036685.2
1159 aa
AgaP_AGAP003568,  A.gambiae
AgaP_AGAP003568
XP_562412.4
959 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

A neural circuit for memory specificity and generalization.
Xu W & Südhof TC. Science 339, 1290-5 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
COesterase (pfam00135)
  Carboxylesterase family.
Aes (COG0657)
  Esterase/lipase [Lipid metabolism].
Esterase_lipase (cl19094)
  Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nlgn2 includes H.sapiens NLGN2 and R.norvegicus Nlgn2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (9 transcripts, 8 species)
Actinopterygii - bony fishes (9 transcripts, 5 species)
Amniota - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

 

 

 

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