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HomoloGene:4461. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TAB1,  H.sapiens
TGF-beta activated kinase 1/MAP3K7 binding protein 1
NP_006107.1
504 aa
TAB1,  P.troglodytes
TGF-beta activated kinase 1/MAP3K7 binding protein 1
XP_515141.3
494 aa
TAB1,  M.mulatta
TGF-beta activated kinase 1/MAP3K7 binding protein 1
XP_002798398.1
504 aa
TAB1,  C.lupus
TGF-beta activated kinase 1/MAP3K7 binding protein 1
XP_538366.4
666 aa
Tab1,  M.musculus
TGF-beta activated kinase 1/MAP3K7 binding protein 1
NP_079885.2
502 aa
Tab1,  R.norvegicus
TGF-beta activated kinase 1/MAP3K7 binding protein 1
NP_001103446.1
502 aa
TAB1,  G.gallus
TGF-beta activated kinase 1/MAP3K7 binding protein 1
NP_001006240.1
438 aa
tab1,  X.tropicalis
TGF-beta activated kinase 1/MAP3K7 binding protein 1
NP_001016463.1
500 aa
tab1,  D.rerio
TGF-beta activated kinase 1/MAP3K7 binding protein 1
XP_002662286.2
365 aa
AgaP_AGAP002953,  A.gambiae
AgaP_AGAP002953
XP_311946.5
460 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

TAK1-binding protein 1 is a pseudophosphatase.
Conner SH, et al. Biochem J 399, 427-34 (2006).
Immunolocalization of TAK1, TAB1, and p38 in the developing rat molar.
Moriguchi M, et al. Anat Sci Int 86, 69-77 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PP2C (pfam00481)
  Protein phosphatase 2C.
MARVEL (pfam01284)
  Membrane-associating domain.
PP2Cc (cl00120)
  Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tab1 includes H.sapiens TAB1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 8 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (4 transcripts, 4 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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