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HomoloGene:133080. Gene conserved in Catarrhini Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

HLA-C,  H.sapiens
major histocompatibility complex, class I, C
366 aa
PATR-C,  P.troglodytes
major histocompatibility complex, class I, C
366 aa
MAMU-B,  M.mulatta
MHC class I antigen
362 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Phenotypic information for the genes in this entry imported from model organism databases.

Psoriasis, early onset, susceptibility to.

Articles associated with genes and sequences of this homology group.

Association analysis of the HLA-C gene in Japanese alopecia areata.
Haida Y, et al. Immunogenetics 65, 553-7 (2013).
Influence of HLA-C expression level on HIV control.
Apps R, et al. Science 340, 87-91 (2013).
HLA-C polymorphisms in two cohorts of donors for bone marrow transplantation.
Jawdat D, et al. Saudi J Kidney Dis Transpl 23, 467-70 (2012).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MHC_I_C (pfam06623)
  MHC_I C-terminus.
MHC_I (pfam00129)
  Class I Histocompatibility antigen, domains alpha 1 and 2.
MHC_I (cl08246)
  Class I Histocompatibility antigen, domains alpha 1 and 2.
Ig (cl11960)
  Immunoglobulin domain.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (2 transcripts, 2 species)




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