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HomoloGene:133080. Gene conserved in Catarrhini Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

HLA-C,  H.sapiens
major histocompatibility complex, class I, C
NP_002108.4
366 aa
PATR-C,  P.troglodytes
major histocompatibility complex, class I, C
NP_001012441.2
366 aa
MAMU-B,  M.mulatta
MHC class I antigen
NP_001041710.1
362 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Psoriasis, early onset, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Association analysis of the HLA-C gene in Japanese alopecia areata.
Haida Y, et al. Immunogenetics 65, 553-7 (2013).
Influence of HLA-C expression level on HIV control.
Apps R, et al. Science 340, 87-91 (2013).
HLA-C polymorphisms in two cohorts of donors for bone marrow transplantation.
Jawdat D, et al. Saudi J Kidney Dis Transpl 23, 467-70 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MHC_I_C (pfam06623)
  MHC_I C-terminus.
MHC_I (pfam00129)
  Class I Histocompatibility antigen, domains alpha 1 and 2.
MHC_I (cl08246)
  Class I Histocompatibility antigen, domains alpha 1 and 2.
Ig (cl11960)
  Immunoglobulin domain.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (2 transcripts, 2 species)

 

 

 

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