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HomoloGene:14. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

AGT,  H.sapiens
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
NP_000020.1
485 aa
AGT,  P.troglodytes
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
NP_001009032.1
485 aa
AGT,  M.mulatta
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
XP_001107374.2
528 aa
AGT,  C.lupus
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
XP_005618890.1
477 aa
Agt,  M.musculus
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
NP_031454.3
482 aa
Agt,  R.norvegicus
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
NP_602308.1
477 aa
AGT,  G.gallus
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
XP_004935548.1
499 aa
agt,  X.tropicalis
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
XP_002931552.2
502 aa
agt,  D.rerio
angiotensinogen
NP_932329.1
454 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Preeclampsia, susceptibility to.
Hypertension, essential, susceptibility to.
Renal tubular dysgenesis.



Publications
Articles associated with genes and sequences of this homology group.

Blood pressure-renal blood flow relationships in conscious angiotensin II- and phenylephrine-infused rats.
Polichnowski AJ, et al. Am J Physiol Renal Physiol 305, F1074-84 (2013).
AGT M235T polymorphisms and ischemic stroke risk: a meta-analysis.
Liang B, et al. J Neurol Sci 331, 118-25 (2013).
Proteolytic processing of angiotensin-I in human blood plasma.
Hildebrand D, et al. PLoS One 8, e64027 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
SERPIN (cl00137)
  SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
SERPIN (cl00137)
  SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Agt includes H.sapiens AGT and R.norvegicus Agt.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 9 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)

 

 

 

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