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HomoloGene:10428. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

FGF21,  H.sapiens
fibroblast growth factor 21
209 aa
FGF21,  P.troglodytes
fibroblast growth factor 21
209 aa
FGF21,  C.lupus
fibroblast growth factor 21
209 aa
FGF21,  B.taurus
fibroblast growth factor 21
209 aa
Fgf21,  M.musculus
fibroblast growth factor 21
210 aa
Fgf21,  R.norvegicus
fibroblast growth factor 21
208 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

FGF21 mediates the lipid metabolism response to amino acid starvation.
De Sousa-Coelho AL, et al. J Lipid Res 54, 1786-97 (2013).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
FGF (cl00060)
  Acidic and basic fibroblast growth factor family; FGFs are mitogens, which stimulate growth or differentiation of cells of mesodermal or neuroectodermal origin. The family plays essential roles in patterning and differentiation during vertebrate ...

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fgf21 includes H.sapiens FGF21 and R.norvegicus Fgf21.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (2 transcripts, 2 species)




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