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HomoloGene:4509. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NR4A2,  H.sapiens
nuclear receptor subfamily 4, group A, member 2
NP_006177.1
598 aa
NR4A2,  P.troglodytes
nuclear receptor subfamily 4, group A, member 2
XP_003309349.1
598 aa
NR4A2,  M.mulatta
nuclear receptor subfamily 4, group A, member 2
XP_001086719.1
598 aa
NR4A2,  C.lupus
nuclear receptor subfamily 4, group A, member 2
XP_535920.2
598 aa
NR4A2,  B.taurus
nuclear receptor subfamily 4, group A, member 2
NP_001069676.1
598 aa
Nr4a2,  M.musculus
nuclear receptor subfamily 4, group A, member 2
NP_001132981.1
598 aa
Nr4a2,  R.norvegicus
nuclear receptor subfamily 4, group A, member 2
NP_062201.2
598 aa
NR4A2,  G.gallus
nuclear receptor subfamily 4, group A, member 2
XP_422166.2
598 aa
nr4a2,  X.tropicalis
nuclear receptor subfamily 4, group A, member 2
NP_001093678.1
591 aa
nr4a2a,  D.rerio
nuclear receptor subfamily 4, group A, member 2a
NP_001106956.1
598 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Parkinson disease.



Publications
Articles associated with genes and sequences of this homology group.

Expression patterns of Nurr1 in rat retina development.
Li Y, et al. J Mol Histol 43, 633-9 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nr4a2 includes H.sapiens NR4A2 and R.norvegicus Nr4a2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Amphibia - amphibians (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

 

 

 

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